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Online Tests Unit 8

 Unit 8: Inheritance biology
A. Mendelian principles: Dominance, segregation, independent assortment, deviation from Mendelian inheritance.
B. Concept of gene: Allele, multiple alleles, pseudoallele,complementation tests.
C. Extension of Mendelian principles: Codominance, incomplete dominance, gene interactions, pleiotropy, genomic imprinting, penetrance and expressivity, phenocopy, linkage and crossing over, sex linkage, sex limited and sex influenced characters.
D. Gene mapping methods: Linkage maps, tetrad analysis, mapping with molecular markers, mapping by using somatic cell hybrids, development of mapping population in plants.
E. Extra chromosomal inheritance: Inheritance of mitochondrial and chloroplast genes, maternal inheritance.
F. Microbial genetics: Methods of genetic transfers- transformation, conjugation, transduction and sex-duction, mapping genes by interrupted mating, fine structure analysis of genes.
G. Human genetics: Pedigree analysis, lod score for linkage testing, karyotypes, genetic disorders.
H. Quantitative genetics: Polygenic inheritance, heritability and its measurements, QTL mapping.
I. Mutation: Types, causes and detection, mutant types – lethal, conditional, biochemical, loss of function, germinal verses somatic mutants, insertional mutagenesis.
J. Structural and Numerical alterations of chromosomes: Deletion, duplication, inversion, translocation, ploidy and their genetic implications.
K. Recombination: Homologous and non homologous recombination, including transposition, site-specific recombination.

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