Rabies virus hijacks and speed up transport in nerve cells

Rabies virus hijacks and speed up transport in nerve cells

Rabies virus usually transmitted through the bite of an infectedanimal into muscle tissue of the new host. Pathogens travel in theblood can spread throughout the body without much effort, courtesy ofheart’s pumping action. Rabies virus depends on the nerve cellnetwork. The researchers found that rabies virus behaves very similarto NGF that binds p75NTR,both are internalized and subsequently foundin acidic vesicles that move toward the nerve cell body. It wassuggested that p75NTR facilitates the directed fast movement of the
virus. It was also manipulated that axonal transport machinery tofacilitate its own arrival at the cell body, and from there to thecentral nervous system at maximum speed.